Compressed Gas: Classification of Hazard

Use and storage of compressed gases is strictly regulated according to hazard classification. See the Toxic and Hazardous Gas Classifications Chart to identify the hazard class of a particular gas.

Compressed gases are classified as class 1, 2, 3 and 4, with 4 being the highest hazard. Classes are based on the lethal concentration to 50% of test animals (rats) of each gas (LC50). Once you define the Classification of Hazard, view the Requirement Matrix.

Compressed Gas Health HazardDescriptionCriteria
4Gas that under emergency conditions will be lethal.LC 50 for inhalation is less than or equal to 1000 ppm; Flammable gases; flammable cryogenic materials; any liquid or gaseous material that is liquid while under pressure and has a flash point below 22.8 C (73 F) and a boiling point below 37.8 C (100 F); materials that ignites spontaneously when exposed to air.
3Gas that under emergency conditions will cause serious or permanent injury.LC 50 for inhalation is greater than 1000 ppm but less than or equal to 3000 ppm; cryogenic gas that can cause frostbite and irreversible tissue damage; compressed liquefied gases with boiling points at or below -55 C (-66.5 F) that cause frostbite and irreversible tissue damage.
2Gas that under emergency conditions will cause temporary incapacitation or residual injury.
LC 50 for inhalation is greater than 3000 ppm but less than or equal to 5000 ppm; compressed liquefied gases with boiling points at or below -30 C (-22 F) and -55 C (66.5 F) that cause severe tissue damage, depending on length of exposure.
1Gas that under emergency conditions will cause significant irritation.LC 50 for inhalation is greater than 5000 ppm but less than or equal to 10,000 ppm.
NFPA 45 Table B.2.2 and Table B.2.4